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is a novel oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity
and the stimulation can be blocked by a PI3-K inhibitor wortmannin
Chemical Name: 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S
CAS Number: 1743-60-8
5S)-3-amino-5-(trifluoromethyl)piperidin-1-yl)quinoline-8-carbonitrile hydrochloride
CYM-2503 Size:Contact [email protected] for quotation is a novel oral multi-AGCCYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor which potentiates galanin induced IP1 production in vitro. CYM2503 potentiated the galanin stimulated IP1 accumulation in HEK293 cells stably expressing GalR2 receptor, whereas it exhibited no detectable affinity for the (125)I galanin binding site of GalR2 receptor, an effect consistent with that of a positive allosteric modulator. Product information CAS Number: 1308833 36 4
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